Francisco Letelier was born in 1973, in Santiago, Chile. After the overthrow of the elected government by Augusto Pinochet, Francisco and his family fled to the U.S. where his father led a movement to publicize the human rights abuses of Pinochet. This led to his father's assassination by Chilean secret police, which was a turning point for Letelier. He and his brother, José, established the "Brigada Orlando Letelier", and began traveling across the country creating collaborative murals. The mural brigade began as a means to reconcile his feelings, but the process of collaboration and storytelling has since continued to propagate and motivate his work as an artist.