Joined by the common desire to get out of their comfort zones, a new team of Roadtrippers embarks on a cross-country journey to interview innovative Leaders who can provide insight on building a fulfilling life. Roadtripper Jackie has just earned a bachelor's degree in chemistry at the University of Texas, and left her home in Mexico to do so. With her family's high hopes hinging on her success, she seeks to find a balance between her academic demands and outside interests.
After settling into life on the Road (which includes dumping septic tanks and sleeping 3 feet away from each other), the team heads towards Hollywood. There, they meet Dr. Valerie Weiss, a film director who went through the trouble of getting a Ph.D in Biophysics so she could determine whether she really wanted to pursue science or filmmaking. Valerie's decision to set aside her Ph.D shows the Roadtrippers that it's never too late to alter your course.
Outside of San Francisco, the team arrives at the Jelly Belly factory to meet with Elise Benstein, a food scientist who develops new Jelly Belly flavors. Elise encourages the Roadtrippers to be open to unplanned opportunity; after all, she never would have thought her job would consist of making Root Beer-flavored candy, but she loves it. From California, the crew winds east to Arizona, where they meet with Deon Clark, a nuclear engineer. Deon joined the navy as a teenager to escape the drugs and violence of his neighborhood, and stresses the importance of rejecting peer pressure.
In Texas, the Roadtrippers head to the Texas Instruments headquarters to meet Process Integration Engineer Byron Williams. Byron shares his struggle with self-doubt that almost stopped him from pursuing a career in science, and encourages the Roadtrippers to re-frame challenge as a motivator. Later, the crew heads to the ATT Foundry to speak with Senior Marketing Manager Tracy Parrish. Tracy discusses her switch from engineering to teaching, and helps Megan overcome her anxiety about teaching STEM subjects. The team ends the week at the National Space Biomedical Research Facility in Houston.
Leaving Houston, the team takes a brief hiatus from interviews with a 2-day drive to Chicago that allows them to reflect on the experience thus far. Once in the Windy City, they find themselves speaking with Zach Kaplan, the CEO and Co-founder of Inventables, a company that connects product developers with novel materials. Zach recounts the many rejections he's been dealt over the years, emphasizing perseverance in the face of challenge. Next, the team heads to Chicagoland Skydive to meet with skydiving instructor Ward Hessig.
As they enter the 5th week of their 7-week Roadtrip, the team reflects on how comfortable they've become with the unpredictable eccentricities of the Road. Megan, who is naturally wired to adhere to routine, is learning to embrace uncertainly, and this helps her cope with an influx of job rejections. In New York, the team's interview with Radiolab radio host Jad Abumrad serves to reinforce Megan's newfound acceptance of the unknown.
In New York City, the team meets with Mariette DiChristina, Editor-in-Chief of Scientific American, who was able to combine her interests in writing, science, and art into a meaningful career. Mariette urges the Roadtrippers to incorporate their passions into their work-even if they face criticism from others. Moving north, the Roadtrippers arrange a visit with Vicki Smith, a game designer at Vicarious Visions. Vicki shares her circuitous route to game design, explaining that she initially abandoned her own dreams in favor of following her parents' expectations.
After traveling over 5,000 miles in 45 days, the Roadtrippers reach Massachusetts for the final week of their journey. There, they meet with Jeremy England, an MIT biophysicist, and Juan Enriquez, the CEO of Biotechnonomy LLC. Change is the topic of discussion with Juan, who tells the Roadtrippers to 'scare the hell' out of themselves sometimes because stagnancy is the enemy of personal growth. Moving onto the last interview of the trip, the Roadtrippers meet with Lydia Villa-Komaroff, an internationally-acclaimed molecular biologist and Chief Scientific Officer at CytonomeST.